CLINICAL PROFILE AND RESISTANCE PATTERN IN ACINETOBACTER BACTEREMIA IN A TERTIARY CARE CENTRE

Abstract

Introduction: Acinetobacter causes deadly hospital acquired infections. This is study was planned to identify the clinical and resistance profile, outcome and mortality predictors of acinetobacter bacteremia in a tertiary care centre in north Kerala.

Methods: retrospective observational study. Data obtained from case records, microbiology culture reports and by interviewing primary care team of each patient

Result: A total of 90 cases positive blood culture reports were collected and required data obtained from 50. 27 cases were analyzed. Resistance was found to be respectively 92% to cephalosporin, 77% to ciprofloxacin and 41% to amikacin. 38% isolates were multidrug resistant. Acinetobacter bacteremia was mostly due to VAP, CLABSI, severe skin infections and neutropenic sepsis.

Conclusion: Acinetobacter bacteremia has an overall mortality rate of 44%, with 75% mortality in VAP presentation. 38% of acinetobacter isolates were multidrug resistant. Most of the patients had malignancies, Diabetes Mellitus or cirrhosis as risk factors.