SALIVARY GLAND MALFUNCTION

Authors

DOI:

https://doi.org/10.55489/njmr.13032023933

Keywords:

Xerostomia, Sjogren’s Syndrome, Sialorrhea

Abstract

This paper goes into great depth on the prevalent health issue of dry mouth. The major salivary glands secrete the total amount 0f 95% saliva. The saliva is composed of both organic and inorganic compounds. The quality of saliva is just as important as quantity when it comes to oral health and well-being. There will be extensive coverage on the many functions and qualities of saliva as well as its role in oral health as well as the important factors that influence salivary production. In this study saliva's role in the development of caries and the formation of bacterial plaque will be examined. There is an initial definition of dry mouth and then an investigation of its prevalence. Following is a list of the most prevalent causes of dry mouth. We will go into why dry mouth is such an issue in the following part. Finally, we will go through how to diagnose and treat dry mouth.

References

Barbe, A.G. Medication-induced xerostomia and hyposalivation in the elderly: culprits, complications, and management. Drugs & aging 2018; 35(10): 877-885. Doi: https://doi.org/10.1007/s40266-018-0588-5 PMid:30187289

Stankeviciene, I., Puriene, A., Mieliauskaite, D., Stangval-taite-Mouhat, L, Aleksejuniene, J. Detection of xerostomia, Sicca, and Sjogren's syndromes in a national sample of adults. BMC oral health 2021: 21(1):1-8. Doi: https://doi.org/10.1186/s12903-021-01917-1 PMid:34706704 PMCid:PMC8555192

Botelho, J., Machado, V., Proença, L., Oliveira, M.J., Cava-cas, M.A., Amaro, L., Águas, A. and Mendes, J.J. Perceived xerostomia, stress and periodontal status impact on elderly oral health-related quality of life: Findings from a cross-sectional survey. BMC Oral Health 2020; 20(1):1-9. Doi: https://doi.org/10.1186/s12903-020-01183-7 PMid:32650751 PMCid:PMC7350690

Grønhøj, C., Jensen, D.H., Vester-Glowinski, P., Jensen, S.B., Bardow, A., Oliveri, R.S., Fog, L.M., Specht, L., Thom-sen, C., Darkner, S. and Jensen, M., 2018. Safety and efficacy of mesenchymal stem cells for radiation-induced xerostomia: a randomized, placebo-controlled phase 1/2 trial (MESRIX). International Journal of Radiation Oncology* Biology* Physics 2018;101(3):581-592. Doi: https://doi.org/10.1016/j.ijrobp.2018.02.034 PMid:29678523

Nardone, V., Tini, P., Nioche, C., Mazzei, M.A., Carfagno, T., Battaglia, G., Pastina, P., Grassi, R., Sebaste, L., Pirtoli, L. Texture analysis as a predictor of radiation-induced xerostomia in head and neck patients undergoing IMRT. La radiologia medica 2018;123(6):415-423. Doi: https://doi.org/10.1007/s11547-017-0850-7 PMid:29368244

Bulthuis, M.S., Jan Jager, D.H. and Brand, H.S. Relationship among perceived stress, xerostomia, and salivary flow rate in patients visiting a saliva clinic. Clinical Oral Investigations 2018; 22(9): pp.3121-3127. Doi: https://doi.org/10.1007/s00784-018-2393-2 PMid:29520470 PMCid:PMC6224012

Marín C. Díaz-de-Valdés L. Conejeros C. Martínez R. and Niklander S. 2021. Interventions for the treatment of xerostomia: A randomized controlled clinical trial. Journal of Clinical and Experimental Dentistry 2021;13(2):e104. Doi: https://doi.org/10.4317/jced.57924 PMid:33574994 PMCid:PMC7864369

Baldini, C., Ferro, F., Mosca, M., Fallahi, P. and Antonelli, A., 2018. The association of Sjögren syndrome and auto-immune thyroid disorders. Frontiers in Endocrinology 2018; 9:121. Doi: https://doi.org/10.3389/fendo.2018.00121 PMid:29666604 PMCid:PMC5891591

Bowman S.J. Primary Sjögren's syndrome. Lupus 2018; 27 (1_suppl):32-35. Doi: https://doi.org/10.1177/0961203318801673 PMid:30452329

Mavragani, C.P. and Moutsopoulos, H.M. Drs. Mavragani and Moutsopoulos reply. The Journal of Rheumatology 2020;47(1):158-158. Doi: https://doi.org/10.3899/jrheum.190837 PMid:31523045

Ozek, D., Kemer, O.E. and Omma, A. Association between systemic activity ındex and dry eye severity in patients with primary Sjögren syndrome. Arquivos Brasileiros de Of-talmologia 2018:82:45-50. Doi: https://doi.org/10.5935/0004-2749.20190005 PMid:30403265

Monsalve, D.M. and Anaya, J.M. With minor salivary gland biopsy in Sjögren syndrome, is a negative result possible?. The Journal of Rheumatology 2020;47(3):310-312. Doi: https://doi.org/10.3899/jrheum.190743 PMid:32115432

Adadan Güvenç I. Sialorrhea: A Guide to Etiology, Assessment, and Management [Internet]. Salivary Glands - New Approaches in Diagnostics and Treatment. IntechOpen; 2019. Doi: https://doi.org/10.5772/intechopen.82619

Miller, N., Walshe, M. and Walker, R.W. Sialorrhea in Parkinson's Disease: Prevalence, impact and management strategies. Research and Reviews in Parkinsonism. 2019; 9:17-28. Doi: https://doi.org/10.2147/JPRLS.S177409

Kalmar C.L. Patel V.A. Zapatero Z.D. Kosyk M.S. Taylor J.A. and Swanson J.W. 2021. Submandibular Gland Excision in Pediatric Patients. Journal of Craniofacial Surgery 2021; 32(8): 2656-2659. Doi: https://doi.org/10.1097/SCS.0000000000007887 PMid:34727467

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Published

2023-09-30

How to Cite

Chaudhry, S., & Ehtesham, Z. (2023). SALIVARY GLAND MALFUNCTION. National Journal of Medical Research, 13(03), 99–102. https://doi.org/10.55489/njmr.13032023933

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Section

Review Article