A Case Control Study of Vitamin D Levels in Chronic Obstructive Pulmonary Disease Patients and Healthy Volunteers in South Gujarat, India

Kunal A Patel; Parth H Patel; Manan P Vaid; Vinod Dandge

doi:10.55489/njmr.12042022931

Authors

Kunal A Patel Surat Municipal Institute of Medical Education and Research, Surat, India
Parth H Patel Surat Municipal Institute of Medical Education and Research, Surat, India
Manan P Vaid Surat Municipal Institute of Medical Education and Research, Surat, India
Vinod Dandge Surat Municipal Institute of Medical Education and Research, Surat, India

DOI:

https://doi.org/10.55489/njmr.12042022931

Keywords:

Vitamin D, COPD, PFT, BMI, Chemiluminescence Immunoassay (CLIA) technique

Abstract

Introduction: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) programme states that COPD is a common, treatable, and preventable disease that is characterized by a persistent airflow restriction that usually progresses and is connected to an exaggerated chronic inflammatory response in the airways and the lung to harmful particles or gases. The combined severity of a patient's co-morbid illnesses and exacerbations increases. The purpose of the study was to assess the vitamin D status of COPD patients and healthy participants.

Methodology: This case-control study was conducted among 75 cases and 75 control at the Surat Municipal Institute of Medical Education and Research General Medicine department.

Result: The mean vitamin D of subjects in cases was 32.21 ± 12.68 and it was 52.05 ± 1.99 in controls. The difference in vitamin D between the two groups was statistically significant (P Value<0.001).

Conclusion: COPD patients had lower amounts of vitamin D. As COPD severity increases, vitamin D levels decrease. Along with a rise in COPD exacerbations, vitamin D levels are also decreasing.

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