STUDY OF TOPICAL PLACENTAL EXTRACT VERSUS POVIDONE IODINE AND SALINE DRESSING IN VARIOUS DIABETIC WOUNDS

Abstract

Objective: The study was conducted with an objective to compare topical placental extract versus povidone iodine and saline dressing in various diabetic wounds.

Method: 60 cases of diabetic wound included which was admitted in SMIMER during September 2010 to august 2012. After complete debridement of wound 30 cases were applied povidone iodine and normal saline, and rest 30 case were applied placental extract till second surgery or wound treated. Outcome was compared in form of healing rate, infection clearance; time of second surgery; hospital stay and duration of treatment. Approval for this study was taken from IEC of the institute.

Result: In study average duration on complete granulation tissue in placental extract dressing is 15.2 day in comparison to povidone iodine which had 24.46 day. In placental group 12 cases treated conservatively and 18 cases needed surgical intervention in comparison to povidone group in which result was 10 cases and 20 cases respectively. Total duration of treatment and hospital stay is less in placental group in comparison to povidone group.

Conclusion: Diabetics are predisposed to development of foot lesions. It increases rate of infection mainly due to higher glucose concentration. Longer the duration of diabetes are more prone for surgical complication. In study, the use of placental extract increases a rate of wound healing due to presence of amino acids, vitamins, nucleotides in it. Patients have early recovery of average 7-10 days.