EVALUATION OF NEUTROPHIL TO LYMPHOCYTE RATIO AS AN INDICATOR OF PRESENCE OF CORONARY ARTERY DISEASE IN DIABETIC PATIENTS

Authors

  • Safak Sahin Gaziosmanpasa University, School of Medicine, Tokat Turkey
  • Savas Sarikaya Bozok University, School of Medicine, Yozgat Turkey
  • Lutfi Akyol3 Bozok University, School of Medicine, Yozgat Turkey
  • Fatih Altunkas Gaziosmanpasa University, School of Medicine, Tokat Turkey
  • Kayihan Karaman Gaziosmanpasa University, School of Medicine, Tokat Turkey

Keywords:

Coronary artery disease, diabetes mellitus, neutrophil to lymphocyte ratio

Abstract

Introduction: Cardiovascular disease (CVD) is the leading cause of death in type 2 diabetes mellitus (DM). DM is a substantial risk factor in atherosclerotic cardiovascular disease. We aimed to investigate relationship between the presence of established neutrophil to lymphocyte ratio (NLR) and coronary artery disease (CAD) in DM.

Methods: 104 diabetic patients who had coronary lesion with a diameter stenosis of at least 50% and 64 diabetic patients who had normal coronary anatomy matched with age and sex were retrospectively selected and classified CAD (+) and CAD (-) group respectively. Baseline NLR in two groups was compared.

Results: NLR was higher in CAD (+) group compared to group without CAD (-) (2.69±1.74 vs. 1.98±.85, p<0.001). C reactive protein (CRP) was higher in CAD (+) group compared to group without CAD (-) (1.71±99 vs. 1.38±.99 p=0.02). Multivariate analysis indicated CRP and NLR were an independent indicator of presence of CAD in diabetic patients (Odds ratio: 1.405, %CI: 1.035-1.908, p=0.029 and odds ratio: 1.759, %CI: 1.226-2.525, p=0.002 respectively).

Conclusion: NLR was higher in diabetic patients with angiographically proven CAD compared to those without CAD. NLR may be a useful marker to predict the presence of CAD in type 2 diabetic patients.

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Published

2013-12-31

How to Cite

Sahin, S. ., Sarikaya, S., Akyol3, L., Altunkas, F. ., & Karaman, K. . (2013). EVALUATION OF NEUTROPHIL TO LYMPHOCYTE RATIO AS AN INDICATOR OF PRESENCE OF CORONARY ARTERY DISEASE IN DIABETIC PATIENTS. National Journal of Medical Research, 3(04), 300–303. Retrieved from https://njmr.in/index.php/file/article/view/655

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Section

Original Research Articles