THE EFFECT OF VITAMIN-D PROPHYLAXIS ON SEVERITY OF ASTHMA

Abstract

Introduction: Asthmatic (case) children had more vitamin D deficiency compared to other (control) children and strong correlation between vitamin D level and severity of asthma symptoms.

Method: A prospective hospital based interventional study was conducted on bronchial asthmatic patients(5-17 years)to find out the role of vitamin D prophylaxis in severity and exacerbation.80 cases were included in the study. Participants were divided in 2 groups-Intervention arm-patients taking vitamin-D capsules Control arm-patients not taking vitamin-D capsules(placebo).At the end of 6 months both groups were compared to look for changes in their severity and number of exacerbation of asthma.

Results: In our study there is slight improvement in severity of asthma in both group till 3 month, at the end of 6 month there is improvement of ACTS score more in case group compared to control group. There is decrease emergency room visit more in case group compared to control group, in hospital admission in both groups and in reliever medication use more in case group compared to control group.

Conclusion: Thus, we conclude that Vitamin-D has significant improvement in severity of asthma, exacerbation of asthma and asthma control test score in case group compared to control group at the end of 6 months. So, we recommend to use vitamin D in asthmatic paediatric cases.