VARIATION IN RESULTS OF CONVENTIONAL DIAGNOSTIC TEST OF TUBERCULOSIS IN HIV POSITIVES

Abstract

Introduction: TB and HIV co-infection are associated with special diagnostic and therapeutic challenges. This study was conducted to detect variation in sputum AFB and Montoux test in TB HIV positives.

Methodology: Current study was a cross sectional study comprises of all HIV patients attending the ART centre. List of HIV positive patients diagnosed with tuberculosis form sampling frame. Total 100 HIV positive patients diagnosed with Tuberculosis and having age more than or equal to 18 years were included in the study.

Results: Out of total 100 patients, 60% were having Pulmonary Tuberculosis and 40 patients were diagnosed with Extrapulmonary Tuberculosis. Age group of 21 to 40 years represents around 49% of patients. Out of total 60 pulmonary TB patients, only 16 (26.7%) shows positive test result on sputum AFB. On Montoux test, 88% patients show negative result and only 1% shows induration ≥ 10 mm.

Conclusion: The study reveal that in HIV TB coninfection results of conventional tests like AFB examination may varied with more sputum negative among pulmonary TB. Majority of patients were tuberculin non-reactive.