A STUDY ON COMPARISON OF INTRAVENOUS BUTORPHANOL WITH INTRAVENOUS FENTANYL FOR PREMEDICATION IN GENERAL ANESTHESIA

Authors

  • Hemangini M Patel Government Medical College, Surat
  • Bansari N Kantharia Government Medical College, Surat

Keywords:

Premedicant, fentanyl, butorphanol, general anesthesia

Abstract

Background: An ideal premedicant drug is anxiolytic, sedative, amnesic, reduces salivary and respiratory tract secretions, analgesic as well as residual post-operative analgesia. The present study was undertaken to compare the effects of intravenous butorphanol and intravenous fentanyl as a premedicant drug in general anesthesia.

Methodology: A comparative study between butorphanol and fentanyl was conducted in 100 patients of either sex at Government Medical College, Surat who belong to ASA physical status I or II, in the age group of 18-65 years. Post-operatively respiratory rate, tidal volume, sedation score, oxygen saturation and assessment of pain score was done in the recovery room.

Results: When comparing both the groups the patients in the butorphanol group were found to be more sedated upto 60 minutes postoperatively. The difference between the two was statistically significant (p<0.001). In group F, 82% patients had analgesia for 60-120 minutes while remaining 18% of patients had analgesia for 121-180 minutes. In group F, 44% patients had analgesia for 121-180 minutes while 56% of patients had analgesia for 181-240 minutes. In group F, 82% patients had pain (VAS ≥5) by 30 minutes in the postoperative period whereas none of the patients in Group B had significant pain (VAS ≥5) by 30 minutes.

Conclusion: We conclude that Butorphanol 20 µg/kg gives better attenuation of the hemodynamic response, longer duration of postoperative pain relief, without producing excessive sedation and with negligible side effects in comparison with fentanyl 1 µg/kg when given intravenously as premedicant for general anesthesia.

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Published

2016-03-31

How to Cite

Patel, H. M. ., & Kantharia, B. N. . (2016). A STUDY ON COMPARISON OF INTRAVENOUS BUTORPHANOL WITH INTRAVENOUS FENTANYL FOR PREMEDICATION IN GENERAL ANESTHESIA. National Journal of Medical Research, 6(01), 89–91. Retrieved from https://njmr.in/index.php/file/article/view/324

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Section

Original Research Articles