ASSOCIATION OF H. PYLORI INFECTION WITH GASTRODUODENAL DISEASE: A CROSS SECTIONAL STUDY FROM MYSURU, INDIA

Abstract

Introduction: In developing countries like India, Helicobacter pylori related gastritis is a major health ailment. This study was aimed to explore the prevalence of H. pylori infection in patients undergoing upper gastrointestinal endoscopy and its association with the various gastroduodenal diseases.

Methods: This study cross sectional includes 158 patients both male and females patients attending Gastroenterology OPD at JSS Hospital, Mysuru with symptoms suggestive of gastro duodenal diseases. They were subjected to upper gastrointestinal endoscopy and investigated for H. pylori infection through histopathological examination. Data analysis was carried out using SPSS for Windows version 16.0.

Results: Prevalence of H. pylori was more in male (78%) population compared to females (66%). Majority of the patients 97 (61.6%) out of 158 were in the age group of 31-60 yrs. Majority of H-pylori positive patients were found to be having H-pylori density 1+ (44.9%). Majority of patients was diagnosed to have duodenal ulcer (25.3%), gastric ulcer (21.5%) and gastric erosions (17.7%).

Conclusion: From this study, we concluded that age related prevalence is more in relatively younger age group than elderly and prevalence is more in males. We also noticed that associations of H-pylori infection with gastric erosions and duodenal ulcers were statistically significant.