Pelvic Congestion Syndrome with Enhanced Myometrial Vascularity Presenting as Abnormal Uterine Bleeding in A Nulli- Parous Women: Case Report
DOI:
https://doi.org/10.55489/njmr.160320261341Keywords:
Pelvic congestion syndrome, Nulliparous, Abnormal uterine bleeding, Dysmenorrhea, Enhanced myometrial vascularity, ProgestinAbstract
Background: Pelvic Congestion Syndrome (PCS) is a chronic pelvic venous disorder commonly associated with chronic pelvic pain, dysmenorrhea, and dyspareunia. Presentation with abnormal uterine bleeding (AUB) is uncommon, particularly when accompanied by enhanced myometrial vascularity (EMV).
Case Presentation: Here, we report a rare case of Pelvic Congestion Syndrome with Enhanced Myometrial Vascularity in a young nulliparous woman presenting with prolonged AUB following misoprostol-induced expulsion of a nonviable twin pregnancy.
Conclusion: This case highlights an unusual presentation of PCS with concomitant enhanced myometrial vascularity, manifesting as prolonged abnormal uterine bleeding after pregnancy loss. Comprehensive evaluation using Doppler ultrasonography, MRI, and laparoscopy can facilitate accurate diagnosis, while progestin therapy may provide effective symptom control in selected cases.
References
1. Antignani PL, Lazarashvili Z, Monedero JL, Ezpeleta SZ, Whiteley MS, et al. Diagnosis and treatment of pelvic congestion syndrome: UIP consensus document. Int Angiol. 2019 Aug;38(4):265-283. DOI: https://doi.org/10.23736/S0392-9590.19.04237-8 PMid:31345010
2. Park SJ, Lim JW, Ko YT, Lee DH, Yoon Y, Oh JH,et al. Diagnosis of pelvic congestion syndrome using transabdominal and transvaginal sonography. AJR Am J Roentgenol. 2004 Mar;182(3):683-688. DOI: https://doi.org/10.2214/ajr.182.3.1820683 PMid:14975970
3. Beard RW, Reginald PW, Wadsworth J. Clinical features of women with chronic lower abdominal pain and pelvic congestion. Br J Obstet Gynaecol. 1988 Feb;95(2):153-161. DOI: https://doi.org/10.1111/j.1471-0528.1988.tb06845.x PMid:3349005
4. Raffetto JD, Qiao X, Beauregard KG, Khalil RA. Estrogen receptor-mediated enhancement of venous relaxation in female rats: Implications of sex-related differences in varicose veins. J Vasc Surg. 2010 Apr;51(4):972-981. DOI: https://doi.org/10.1016/j.jvs.2009.11.074 PMid:20347696 PMCid:PMC2847594
5. Jurga-Karwacka A, Karwacki GM, Schoetzau A, Zech CJ, Heinzelmann-Schwarz V, Schwab FD. A forgotten disease: Pelvic congestion syndrome as a cause of chronic lower abdominal pain. PLoS One. 2019 Apr 2;14(4):e0213834. DOI: https://doi.org/10.1371/journal.pone.0213834 PMid:30939134 PMCid:PMC6445463
6. Kuo CH, Martingano DJ, Singh P. Pelvic Congestion Syndrome. [Updated 2025 Jan 19]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK560790/
7. Gavrilov S, Karalkin A, Mishakina N, Efremova O, Grishenkova A. Relationships of Pelvic Vein Diameter and Reflux with Clinical Manifestations of Pelvic Venous Disorder. Diagnostics (Basel). 2022 Jan 7;12(1):145. DOI: https://doi.org/10.3390/diagnostics12010145 PMid:35054312 PMCid:PMC8774919
8. Bałabuszek K, Toborek M, Pietura R. Comprehensive overview of the venous disorder known as pelvic congestion syndrome. Ann Med. 2022 Dec;54(1):22-36. DOI: https://doi.org/10.1080/07853890.2021.2014556 PMid:34935563 PMCid:PMC8725876
9. Ni T, Friedman I, Smith J, Liu B, Melchior M, Brown AD. Pelvic venous disorders in women: Diagnosis and management for gynecologists. Int J Gynecol Obstet. 2026;00:1-10. DOI: https://doi.org/10.1002/ijgo.70955 PMid:41830219
10. Koo S, Fan CM. Pelvic congestion syndrome and varicosities.Tech Vasc Interv Radiol. 2014 Jun;17(2):90-95. DOI: https://doi.org/10.1053/j.tvir.2014.02.005 PMid:24840963
11. Elagwany AS. Pelvic Congestion, Enhanced Myometrial Vascularity, AVM Versus Normal Vasculature Variants: A Confusing Diagnosis Regarding Uterocervical Vasculature. Indian J Surg Oncol. 2020 Sep;11(Suppl 2):323-326. DOI: https://doi.org/10.1007/s13193-020-01232-1 PMid:33364729 PMCid:PMC7732934
12. Galea M, Brincat MR, Calleja-Agius J. A review of the pathophysiology and evidence-based management of varicoceles and pelvic congestion syndrome. Hum Fertil (Camb). 2023 Dec;26(6):1597-1608. DOI: https://doi.org/10.1080/14647273.2023.2212846 PMid:37190955
13. Cheong YC, Smotra G, Williams AC. Non-surgical interventions for the management of chronic pelvic pain. Cochrane Database Syst Rev. 2014 Mar 05;2014(3):CD008797. DOI: https://doi.org/10.1002/14651858.CD008797.pub2 PMid:24595586 PMCid:PMC10981791
14. Soysal ME, Soysal S, Vicdan K, Ozer S. A randomized controlled trial of goserelin and medroxyprogesterone acetate for the treatment of pelvic congestion. Hum Reprod. 2001 May;16(5):931-939. DOI: https://doi.org/10.1093/humrep/16.5.931 PMid:11331640
15. Farquhar CM, Rogers V, Franks S, Pearce S, Wadsworth J, Beard RW. A randomized controlled trial of medroxyprogesterone acetate and psychotherapy for the treatment of pelvic congestion. Br J Obstet Gynaecol. 1989 Oct;96(10):1153-1162. DOI: https://doi.org/10.1111/j.1471-0528.1989.tb03190.x PMid:2531611
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Copyright (c) 2026 Shalini Mishra, Anima Prasad, Gajanan G Patil, Jigarkumar Chaudhari, Annu Malik

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