A Comparative Study Between Collagen Sheet Dressing and Conventional Paraffin Gauze Dressing to Donor Site in Patients Undergoing Split Skin Grafting

Balaji Rajavarman; Raju Manigandan; AS Sangeethapriya; Umesh Raj Somasundaram

doi:10.55489/njmr.150120251040

Authors

Balaji Rajavarman Panimalar Medical College Hospital and Research Institute, Chennai, India
Raju Manigandan Melmaruvathur Adhiparasakthi Institute of Medical Sciences, Melmaruvathur, Tamil Nadu, India
AS Sangeethapriya Melmaruvathur Adhiparasakthi Institute of Medical Sciences, Melmaruvathur, Tamil Nadu, India
Umesh Raj Somasundaram Melmaruvathur Adhiparasakthi Institute of Medical Sciences, Melmaruvathur, Tamil Nadu, India

DOI:

https://doi.org/10.55489/njmr.150120251040

Keywords:

Collagen dressing, Split Skin grafting, Epithelization

Abstract

Introduction: Split skin grafting is a common procedure that causes partial thickness injury, typically treated with paraffin-soaked gauze. Re-epithelialization occurs in two weeks, but complications like pain, infection, and delayed healing can arise. This study aimed to compare collagen sheet dressing with conventional gauze dressing in reducing pain, promoting healing, and preventing infection in donor sites.

Material and Methods: A prospective comparative study was conducted at a tertiary care hospital from December 2021 to January 2024. Fifty patients undergoing split skin graft surgery were assigned to either Group A (collagen sheet) or Group B (paraffin gauze). Outcomes such as pain, re-epithelialization, and infection were compared using descriptive statistics, chi-square, Fischer’s exact, and Student’s t-tests. P<0.05 was considered significant.

Results: The mean age of Group A and Group B was 53.92 and 56.6 years, respectively. Pain scores were significantly lower in the collagen group (P<0.05). Epithelialization on day 10 was higher in the collagen group (85.2±5.09) compared to the conventional group (68.4±8). One patient in the conventional group had an infection, whereas none were observed in the collagen group.

Conclusion: Collagen sheet dressing in split skin grafting donor sites results in reduced pain, faster epithelialization, and lower infection rates.

References

Das S, Singh AI, Singh LO, Sinam N, Singh SN. A comparative clinical study of collagen and paraffin gauze dressing on skin donor site. J Med Soc. 2020 Dec;34(3):162. DOI: https://doi.org/10.4103/jms.jms_25_21 DOI: https://doi.org/10.4103/jms.jms_25_21

Braza ME, Fahrenkopf MP. Split-Thickness Skin Grafts. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publish-ing; 2024 [cited 2024 Oct 24]. Available from: http://www.ncbi.nlm. nih.gov/books/NBK551561/

Sreekumar NC, Bhandari PL, Praveen N. Comparative study of collagen and paraffin gauze dressing on skin graft donor site. Indian J Burns. 2015 Dec;23(1):81. DOI: https://doi.org/10.4103/0971-653X.171663 DOI: https://doi.org/10.4103/0971-653X.171663

Bendre DM. Role Of Collagen Dressing Over Donor Site In Cas-es Of Split Skin Grafting. Clin Med. 2022;09(08).

Sharma DJ, Mishra B, Arora C. In search of ideal donor site wound dressings. Int Surg J. 2020 Aug 27;7(9):3012-6. DOI: https://doi.org/10.18203/2349-2902.isj20203786 DOI: https://doi.org/10.18203/2349-2902.isj20203786

Ayaz SM. Evaluation of Effectiveness of Collagen Dressing in Healing of Split Skin graft Donor Site Wound.

Dave TJ, A SC, K K. A retrospective study of comparison of collagen dressing versus conventional dressing for skin graft donor site. Int Surg J. 2021 May 28;8(6):1730-3. DOI: https://doi.org/10.18203/2349-2902.isj20211958 DOI: https://doi.org/10.18203/2349-2902.isj20211958

Jain A, Aaudichya A, Rathwa A, Jain P, Patel P. Collagen Dressing Versus Conventional Vaseline Gauze Dressing in Reducing Pain and Infection at the Donor Area for Skin Grafting: A Prospective Interventional Study. Int J Anat Radiol Surg. 2022 Apr 1;11. DOI: https://doi.org/10.7860/IJARS/2022/51192.2776 DOI: https://doi.org/10.7860/IJARS/2022/51192.2776

Pathak AK. A Comparative Clinical Study of Collagen and Paraf-fin Gauze Dressing on Skin Donor Site in Shyam Shah Medical College Rewa, Madhya Pradesh. Int J Pharm Clin Res. 2023; 15 (5); 1279-1284

Ayaz SM, Pai MV, Rai BKS. Comparative Study Between Collagen Dressing and Conventional Vaseline Gauze Dressing in Healing of Donor Site Wound in Split Skin Graft. IOSR Journal of Dental and Medical Sciences 2016; 15(10):34-41.

Ramesh BA, Jayalakshmi BK, Mohan J. A Comparative Study of Collagen Dressing versus Petrolatum Gauze Dressing in reducing Pain at the Donor Area. J Cutan Aesthetic Surg. 2017 Mar;10(1):18. DOI: https://doi.org/10.4103/JCAS.JCAS_110_16 PMid:28529416 PMCid:PMC5418976 DOI: https://doi.org/10.4103/JCAS.JCAS_110_16

Singh O, Gupta S, Soni M, Moses S, Shukla S, Mathur R. Collagen Dressing Versus Conventional Dressings in Burn and Chronic Wounds: A Retrospective Study. J Cutan Aesthetic Surg. 2011 Jan 1;4:12-6. DOI: https://doi.org/10.4103/0974-2077.79180 PMid:21572675 PMCid:PMC3081477 DOI: https://doi.org/10.4103/0974-2077.79180

Gore MA, Umakumar K, Iyer SP, Gore MA, Umakumar K, Iyer SP. Polyethylene Surgical Drape Dressing for Split Thickness Skin Graft Donor Areas. In IntechOpen; 2013 [cited 2024 Oct 24]. Available from: https://www.intechopen.com/chapters/42570

Asokan A, Chittoria R, Pandey S, Mohapatra D, MT F, K.S D. Autologous Platelet Rich Plasma versus Collagen Dressing in Promoting Healing of Donor Site of Skin Graft. New Indi-an J Surg. 2017 Jan 1;8:477-81. DOI: https://doi.org/10.21088/nijs.0976.4747.8417.3

Chowdhry SA. Use of oxidized regenerated cellulose (ORC)/collagen/silver-ORC dressings to help manage skin graft donor site wounds. JPRAS Open. 2019 Dec;22:33-40. DOI: https://doi.org/10.1016/j.jpra.2019.08.001 PMid:32158895 PMCid:PMC7061655 DOI: https://doi.org/10.1016/j.jpra.2019.08.001

Fleck CA, Simman R. Modern Collagen Wound Dressings: Function and Purpose. J Am Coll Certif Wound Spec. 2011 Aug 1;2(3):50. DOI: https://doi.org/10.1016/j.jcws.2010.12.003 PMid:24527149 PMCid:PMC3601889 DOI: https://doi.org/10.1016/j.jcws.2010.12.003