A STUDY OF METALLO-BETA-LACTATAMASE PRODUCING PSEUDOMONAS AERUGINOSA IN CLINICAL SAMPLES OF S.S.G. HOSPITAL

Authors

  • Mehul S Chaudhari Govt. Medical College, Baroda
  • Tanuja B Javadekar Govt. Medical College, Baroda
  • Govind Ninama Govt. Medical College, Baroda
  • Govind Ninama Govt. Medical College, Baroda
  • Jivraj Damor Govt. Medical College, Baroda

Keywords:

metallo-beta-lactatamase, producing, pseudomonas aeruginosa, drug resistence

Abstract

Introduction: Pseudomonas spp. is common pathogen causing nosocomial infection. Acquired drug resistance is frequent in nosocomial isolates of Pseudomonas spp. Acquired metallo-β-lactamases (MBL) in pseudomonas spp. have recently emerged as one of the most worrisome resistance mechanism because of their capacity to hydrolyze all beta-lactam antibiotics including penicillins, cephalosporins and carbapenems, with the exception of aztreonam.

Aim: To detect metallo-β-lactamase producing isolates of Pseudomonas aerugenosa from various clinical samples from patients admitted in our hospital.

Material and methods : In this studyt we studied the prevalence, following standard methods of isolation and identification techniques of these bacteria from clinical materials

Source : Samples of patients from different wards of S.S.G.Hosital are proceeded in Microbiology department , Medical College and S.S.G.Hospital Baroda.

Results: Of total study of 150 isolates of Pseudomonas aeruginosa, 8 isolates are resistance to Imipenem . Of 8 samples , all are producing Metallo-Beta-Lactamase enzyme.

Conclusion :Infection cause by MBL (metallo-β-lactamase) positive isolates of Pseudomonas aerugenosa is important to identify because it poses not only therapeutic problem, but also a serious concern for infection control management.

Downloads

Published

2011-12-31

How to Cite

Chaudhari, M. S. ., Javadekar, T. B., Ninama, G. ., Ninama, G., & Damor, J. . (2011). A STUDY OF METALLO-BETA-LACTATAMASE PRODUCING PSEUDOMONAS AERUGINOSA IN CLINICAL SAMPLES OF S.S.G. HOSPITAL. National Journal of Medical Research, 1(02), 60–63. Retrieved from https://njmr.in/index.php/file/article/view/883

Issue

Section

Original Research Articles

Most read articles by the same author(s)