ROLE OF FINE NEEDLE ASPIRATION CYTOLOGY IN PALPABLE BREAST LESIONS AND ITS CORRELATION WITH HISTOPATHOLOGICAL DIAGNOSIS

Abstract

Background: Breast carcinoma is the common malignant lesion in women. Fine needle aspiration cytology has high sensitivity and specificity and is simple, rapid and safe method to diagnose breast lesions.

Materials and methods: A retrospective study was done in department of pathology of C.U.SHAH medical college and hospital of Surendranagar from January 2010 to July 2012. Total 120 FNAC of palpable breast lump was done in pathology department of C.U. SHAH medical college and hospital and correlate it with histopathological findings. All cases are categorized according to risk for cancer into unsatisfactory sample, benign proliferative breast disease without atypia, Benign proliferative disease with atypia, Inflammatory breast disease, suspicious for malignancy and malignant lesions.

Results: Out of 120 cases, 65 cases were benign, 32 malignant, 2 suspicious and 16 were inflammatory breast and 4 were unsatisfactory lesions. Cytological and histopathological correlation found in 114 cases (95.83%) out of 120 cases. Fibroadenoma is the most common benign breast lesion noted in 21-30 years age group, while ductal carcinoma was commonest malignant lesion noted in 41-50 years of age group. The sensitivity and specificity of FNAC were 97.05% and 98.78%

Conclusion: Fine needle aspiration cytology of palpable breast lesions is an effective modality for diagnosis of most of the malignant and benign lesions. Fine Needle Aspiration Cytology is highly sensitive and specific technique for diagnosis of most of the malignant and benign breast lesions.