EFFECT OF MATERNAL OBESITY ON CORD BLOOD GLUCOSE LEVEL OF TERM NEONATES

Abstract

Background: Almost all the countries of the world are facing epidemic of obesity. Occurrence of obesity in pregnant female is also increasing. Obesity changes intrauterine environment for growing fetus leading to metabolic changes in offspring. This study was done to evaluate impact of maternal obesity on fetal glycemic profile.

Aim and Objectives: To compare levels of umbilical cord blood glucose in term neonates born to mother with obesity with that of normal healthy mother.

Methodology: A total of 58 neonates born form obese mother and 78 neonates born from lean healthy mother were recruited in the study after obtaining informed consent of the mother. Maternal pre-pregnancy body mass index (BMI) was noted. Umbilical cord blood glucose was analysed. Data was compiled and statistical analysis was done.

Results: We observed no significant difference between levels of Umbilical cord glucose among cases compared with controls (p>0.05).

Conclusion: Neonates of obese mother may show altered cord blood glucose level compared with those from lean mothers. Such neonates may be more prone to develop metabolic complications in adult life. Identification of such babies at early age and introduction of healthy diet & lifestyle can reduce occurrence of lifestyle diseases.