A STUDY OF PULMONARY FUNCTION TEST IN TYPE 2 DIABETES MELLITUS

Abstract

Introduction: Type 2 Diabetes mellitus is a metabolic disorder that is characterized by high blood glucose in the context of insulin resistance and relative insulin deficiency. These processes play the main role in causing impairments of collagen & elastin cross linkage, which thereby causes reduced elasticity of connective tissue. ^.The presence of abundant connective tissue and micro-vascular circulation in lung raises the possibility that in diabetic patients, lung could also be a “target organ”_.Pulmonary function test is a useful test to assess involvement of lung connective tissues and micro vascular bed in diabetic patients.

Methods: In this study, which was conducted in a tertiary care hospital of South Gujarat, we enrolled 65 subjects who were known cases diabetes mellitus.

Result: Diabetes Mellitus in patients alters Various parameters of PFT like FVC, FEV1 which are reduced while FEV1/FVC increased showed restrictive pattern compared to normal individual.

Conclusion: Diabetes mellitus patients have positive correlation with interpretation of PFT as with HbA1c increases a greater number of patients develop abnormal PFT in which Restrictive pattern is seen more commonly.