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title:Susceptibilities of ESBL-Producing Enterobacteriaeceae To Ertapenem, Meropenem and Piperacillin-Tazobactam

Author:Shah Kinal, Mulla Summaya A

Keywords:Ertapenem, ESBL, Meropenem, E.coli, K .pneumonia

Type:Original Article

Abstract:Objectives: The susceptibilities of ESBL-producing E.coli and K. pneumoniae to ertapenem, meropenem and piperacillin-tazobactam.53 strains of E.coli and K. pneumoniae were studied. Methods: They were originally resistant to ceftazidine. Minimum inhibitory concentration of the strains towards ertapenem, meropenem and piperacillin-tazobactam were determined by Vitek-2 compact system. Results: The MICs of all ertapenem and meropenem for all isolates were <0.5 ?g/ml and <0.25 ?g/ml respectively and MIC of piperacillin-tazobactam was between 4 to 16 ?g/ml. ESBL-producing organisms were more susceptible to ertapenem and meropenem. They were susceptible to piperacillin-tazobactam thus in our hospital ertapenem, meropenem and piperacillin-tazobactam are drugs of choice for them.

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