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title:Comparision of Dexmedetomidine and Magnesium Sulphate as an Adjuvant to Bupivacaine for Transverse Abdominis Plane Block In Caesarean Delivery for Post Operative Analgesia

Author:Bhumika A Munshi, Pragna N Vachhrajani, Mitesh K Patel

Keywords:Transverse abdominis plane block, Bupivacaine, Magnesium sulfate, dexmedetomidine

Type:Original Article

Abstract:"Postoperative pain relief can be achieved by a variety of techniques including peripheral nerve block, paren-teral NSAIDS, epidural analgesia, neuraxial local analgesics. The transverse abdominis plane block is a local anaesthetic block used to provide analgesia to the anterior and lateral abdominal wall. Methods: The prospective randomised study carried out in 90 patients belonging to ASA 1, 2 posted for LSCS and divided into 3 groups,30 patients each. All patients receive TAPP block at the end of surgery. Group B received TAPP block with 18 ml 0.25% bupivacaine 18ml with 2ml NS. Group BM received 0.25% bupivacaine with 1.5ml (150mg) of magnesium sulfate and 0.5ml of NS. Group BD received 20ml of bupivacaine with dexmedetomidine 0.5 mcg/kg with 2ml NS. Results: Combination of 0.25% bupivacaine and 150mg magnesium sulfate and combination of 0.25% bupivacaine and 0.5mcg/kg dexmedetomidine provides longer duration of analgesia compared to 0.25% bupivacaine alone. Conclusion: Maximum duration of analgesia observed with combination of 0.25% bupivacaine and mag-nesium sulfate 150mg.Thus TAPP block when used as a part of multimodal regime provided superior an-algesia up to 48 hours and reduced the need of opioid analgesia following LSCS under spinal anaesthesia. "

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