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title:A Study on Clinical Profile of Patients with Inflammatory Bowel Disease

Author:Sadiqul Islam, Mayank Agarwal, Anjam J Talukdar, Sangitanjan Dutta, Partha P Kalita

Keywords:IBD, CD, UC, CDAI

Type:Original Article

Abstract:Introduction: Inflammatory Bowel Disease (IBD) is an immune mediated chronic intestinal condition. Crohn’s Disease (CD) and Ulcerative Colitis(UC) are the two major types of IBD. Aims and Objectives: i) To study the prevalence of IBD in Gauhati Medical College and Hospital.ii) To study the clinical profile of patients with IBD. Materials and Methods: A total of 38 patients of IBD were enrolled in this prospective observational hospital based study. The study was conducted from July 2014 to June 2015. All patients presenting to the department of Medicine, Gauhati Medical College and Hospital with history suggestive of IBD were evaluated through history taking, clinical evaluation and laboratory investigation as per requirement of the patients. Results: The hospital prevalence of UC was found to be 22.99 and of CD was9.37 per 100,000 persons. Males were more affected than females in both UC and CD. The most common clinical features of UC were rectal urgency, increased frequency of stools, blood in stools, tenesmus, mucus in stools, loose stools and abdominal pain whereas in CD abdominal pain, loose stools, weight loss and mucus in stools were the common clinical presentations. Extraintestinal manifestations were seen in 11.11% of UC patients and 27.27% of CD patients with arthralgia being the most common. Conclusion: Since this was a hospital based study with a small sample size, a larger study recruiting more patients with a longer duration of follow up is necessary for a better understanding of the disease and to arrive at definite conclusion.

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