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title:A Study on Cervical Pap Smear Examination in Patient Living with HIV

Author:B M Jha, Mubin Patel, KomalPatel, Jitendra Patel

Keywords:HIV, Pap smear, patient living with HIV (PLWH)

Type:Original Article

Abstract:Background: Decline in morbidity & mortality due to cervical cancer in developed countries can be mainly attributed to early detection of precancerous & cancerous lesions due to extensive screening programmeof cervical Pap smear examination. HPV infection is a known etiological agent for cervical cancer. HIV infected women are at higher risk of contracting HPV infection due to immune compromised status. Objective: Present study has been undertaken mainly to detect precancerous & cancerous lesions as well as inflammatory lesions in female patients living with HIV & to emphasize the fact that Pap smear examination should be established as a part of routine protocol for examination in these women. Methods: The study was carried out on 407 HIV infected females attending Integrated Counseling &Testing; Centre of government institute. As controls, 200 females (not falling under high risk category), attending the Obstetrics& Gynecology OPD with various gynecological complaints were taken & results were compared. Results: Squamous cell abnormalities were found about four times high as compared to control group(Pvalue <0.05). High incidences of squamous cell abnormalities were noted in patients with high parity (parity three or more). Conlcusion: Regular gynecological examination including Pap smear examinations is highly recommended for HIV infected females.Pap smear examination is a simple, cheap, safe & practical diagnostic tool for early detection of cervical cancer in high risk population.

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