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title:Clinical and laboratory evaluation of patients with febrile thrombocytopenia

Author:Amita A Gandhi, Pankaj J Akholkar

Keywords:Fever, Thrombocytopenia, Malaria, Dengue

Type:Original Article

Abstract:Background: Infection is a common cause of thrombocytopenia. Fever with thrombocytopenia is a common condition that is associated with an increased risk of morbidity and mortality. Infections like Malaria, Dengue, Typhoid and septicaemia are some of the common causes of fever with thrombocytopenia. Methods: 112 patients aged > 18 years with fever and thrombocytopenias were observed for bleeding manifestations. Aims and objectives: To determine the relative frequency of different diseases in fever with thrombocytopenia and to observe the different bleeding manifestations in order of their incidence in fever with thrombocytopenia and their relation with platelet count. Results: Dengue was the commonest cause of fever with thrombocytopenia (26.79%) followed by P.falciparum malaria (20.54%) and P. Vivax malaria (16.07%). Bleeding manifestations were seen in38.40% of patients. 76.74% of patients had patechie/purpura as the commonest bleeding manifestation followed by gum bleeding in 16.28 %. Conclusions: Dengue was the commonest cause of fever with thrombocytopenia. Common Bleeding manifestations were patechie /purpura and gum bleeding.

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