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title:Comparison between Caudal Bupivacaine and Caudal Midazolam for Post Operative Analgesia in Pediatric Patients

Author:Asmita Chaudhary, Vipul Chaudhari

Keywords:Bupivacaine, Midazolam, caudal analgesia, anesthesia

Type:Original Article

Abstract:Objective: To evaluate the efficacy and side effect of caudal Bupivacaine as compared to caudal Midazolam for providing post operative analgesia in children. Material and method: It was a prospective, open label, randomized study on 50 patients aged between 1-12 yrs of American society of anesthesiologist (ASA) grade I and II posted for below umbilical surgery under standardized general anesthesia. After induction, patients were allocated randomly into two groups. Gropup-1 received caudal block with inj. Bupivacaine (0.25%) 1ml/kg and Group-2 received caudal block with inj. Midazolam 50 µg/kg+ saline 1ml/kg. Children were continuously observed in recovery room for 20 minutes after which they were shifted to general ward. In ward OPS (observer pain scale) score was recorded at 0.5,2,4,8,12 and 24 hours after surgery. Result: Pain score was comparable for initial half an hour postoperatively for both the groups but at 2, 4, and 8 hrs postoperatively Group-1 had low OPS compare to Group-2. The overall need for rescue analgesic was lower in Group-1 compare to Group-2. Conclusion: We concluded that analgesic effect was longer and lesser need for rescue analgesic in the postoperative period in Bupivacaine group compare to Midazolam group.

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